There is a risk of applying unneeded Modern Digital Precise Result thinking to such problems.
Remember that your hull (unless made of alum. or steel) is made of "fiber reinforced plastic" or "FRP." The material that Forespar uses for its excellent valves is also FRP.
Epoxy bonds forcefully to this material. You can always just remove the OEM thru hull and patch the hole with layers of glass and epoxy at the normal 12 to 1 cut back. G10 could be used for an inside reinforcing plate, but it would take a wide area of coverage around the hole to approach the strength of the simpler patch done the right way.
Our Series 93 Forespar thruhull seacocks are actually bedded in thickened epoxy, and were installed in the 90's. Changing them out, someday in the future, will involve a hole saw and a grinder. (No so much different than having to remove old thrufulls glued in with 5200...!)
Having the bases be "one with the hull" is a great way to have full structural integrity with no worries about leaks.
If you want to eliminate the OEM thruhulls, you can certainly do so. A short trip to the yard for a day will be needed, and best be done when hauled for a bottom paint job. (IMO, and YMMV)