Yes, did one of mine last year. Make sure its clean of old caulking, and then scrub with soapy water then rinse with water. Mask off the topsides around the window & on the window, both inside and out for easier clean-up, and use the Dow silicone, although I used the Tremco version, of the silicone.
You can also search on the forums to find many other discussions on this.