Hi,
I like to use Prestone and I always buy the full strength, extended life, un-mixed version. I prefer to mix the 50/50 myself. (I'm a suspicious control freak).
My experience has always been that the only thing that depletes in anti-freeze is the water pump lubricant. The alcohol always seems to retain it's ability to remain liquid. I change it about every 4 years.
a. The "water pump lubricant" does not deplete. I'm in engine coolant manufacturing business, and that component lasts at least 10 years (dicarboxylic organic acid). In recreational marine service the only probable failure is contamination with seawater.
b. It is a glycol not an alchohol. Someone is going to quible that it is a double alchohol, but that is a superficial connection. The most likely breakdown products are glycolic and formic acid, which can become a problem in 5-8 years, depending on hours (generally about 8-10000 hours in truck service or bus service, based upon extensive fleet testing).
c. If you blend, use DI water, as required by ASTM and OEM specification. Bad water (containing sulfate, chloride or hardness) is one reason pre-dilute is common.
d. PG (winterization antifreeze) is NEVER used on engines isolated by heat exchangers. The corrosion inhibitor system is nearly absent and all wrong anyway. A diesel truck antifreeze, such as Final Charge or Prestone Heavy Duty, is a good choise. Though you can buy PG engine coolant (Sierra), there is a reason auto OEMs don't use it; it doesn't work as well (slightly inferior heat transfer agent). There is no environmental benifit, and you should recycle the spent coolant anyway.
Read the manual. The advise there will be sound.