I disagree, respectfully, with aiming for slack tide at midday at Hell Gate. I have made this trip several times and have always tried to ride a fair current as suggested by the offshoreblue rule of thumb I linked above. That means leaving Port Washington friday around 5 a.m. and passing under the Throgs Neck Bridge around 5:30.
Also, as others mentioned, bring a chart or have one on a tablet and be sure to pass west of Roosevelt Island.
Also, as others mentioned, bring a chart or have one on a tablet and be sure to pass west of Roosevelt Island.