Interesting to bring this up today as a topic. I was just out solo in Long Beach Harbor yesterday afternoon dialing in a new No. 2 furling genoa in 19 kt true, and up to 25 kt apparent going to weather. Jib only up. I have a 38' ft, 16,000 lb, fractional rig. So, the situation is fresh in my mind.
I didn't put the main up b/c I was lazy; but in that wind it would be tough to get the large main up b/f the head of the boat blew off unless moving fairly fast directly into the wind. Just a little off and the bow falls off rapidly while you're up on deck still trying to get the mainsail up. I really don't think a wheel lock could hold the boat very long. [Off course, the sail is also getting pinned against the shrouds unless you've somehow gotten to the main sheet and eased it, etc.] However, an autopilot works if you move fast. Clearly, you'll have to develop some technique there, etc., if not using an autopilot.
Deploying a furled jib is not hard, but trimming it can be unless you can reach the winch from the steering station, and you have the bicep power to trim at the less-than-optimal angle you're working from. Again; technique. I can just reach the winch handle at its closest point with one hand on the wheel. To crank I have to let go the wheel long enough to get past the distal turning point using my left or right arm; etc. For tacking I need both hands; and I cannot complete it from behind the wheel b/c I cannot trim in the sail on the new tack until I lock the sheet into the self-tailer; insert winch handle, and crank, etc. Meanwhile, who is steering the boat? The wheel lock? I don't think so.
Just a few points here; I could write an essay on the subject. Short version; you need an autopilot; don't leave home without one!