Marco to Keys
Dorothy, First of all, you'll need a good number of charts. No single chart covers this area with enough detail. The whole area from the southwest corner of the mainland to the upper keys is very shallow, and should probably be avoided unless you're familiar with the area. Anchorages, marinas, etc depends on where in the keys you want to go, and whether you want to cruise the bay side or the ocean side. With a little more info, I can provide more specifics. Robert Pancza