Keys route
As someone else has already observed the 410's mast is to tall for the lake route. You can go through Big Spanish Channel but probably not at low water. You can also get into Key Largo canal, but again not at low water. Give the R#2 daymark a wide berth off your starboard side as you go in, the sand bank extends across the direct route. Once past the entrance the water is plently deep, put you'll more than likely bump at low water right at the mouth of the canal. There are several marinas at Key Largo. Further north you can get into Card Sound through Anglefish Creek. Again, I would be careful about low water going in, the controling depth is a ledge in the entrance. Once in Card Sound you can anchor behind Pumpkin Key if you wish. The channel through Cutter Bank is a bit narrow, and the tide will tend to set you to one side or the other, so be on the lookout for it. From there the next obstacle is the Featherbed Bank with two channels through, both fairly wide. The bridges in Miami are high enough you shouldn't have to worry, except the Julia Tuttle on the ICW north of Miami. You can't get under it.