Barrier Coating
If you are barrier coating the epoxy over the screw heads it should be waterproof and you don't need to worry about wicking or moisture. With microfibers they are all randomly oriented so inevitably some of the fibers will be oriented perpendicular (or at a steep angle) to the hull giving the water a wicking path into the epoxy. You were concerned about paint adhesion. Bottom paint is not water proof anyway so presence of moisture is not a factor in adhesion to the surface except when it is coated originally. You just need a good surface for the paint to adhere, the interlux is recommended as a priming coat to help with paint adhesion, you may want to lightly sand the epoxy, slap on a couple coats of the inturlux 2000 if you have any left, then bottom paint over that. When I ground all the paint off my lead keel and sealed it with west epoxy I threw a couple coats of interlux over the epoxy to help with paint adhesion. Why did I seal the lead keel? oxidized lead will not allow paint to adhere well so I sanded it all off (wear a respirator approved for lead dust) put a couple coats of WEST epoxy, used a wire brush to work it into the lead, cure it, then the interlux bottom coat followed by bottom paint. Much less work on haul outs to add a couple coats of paint versus scraping and sanding related to poor adhesion.