Wow Joe, that was pretty specific! Can't get much more detailed then that. Is the wind so reliable there that you know when & where you'll be on a port tack & beam reach?
Yeah... pretty much... this time of year it's predominantly sea breezes that dictate our sailing. Although low pressure systems occasionally give us more southerly winds .... which is great if you are going northwards to Catalina, Newport Beach, Long Beach etc. It's not so much about reliable wind.... but rather putting yourself in a position to take advantage of varying conditions.
So....when you plan a trip northards from San Diego you must always assume the seabreeze phenomenon. If the wind goes southerly at departure time.... well....that's cool... However, if you plan your trip around an anticiated southerly wind... you're likely to be disappointed and will end up motoring most of the way.
Whether you shape your course directly to Catalina or harbor hop up the coast... you must always assume a headwind and adverse current... that would be your worst case scenario.... then you can take advantage of things such as the "catalina eddy" or an Arizona summer monsoon that generates southeasterlies.... if they occur near departure time.
That said.... most San Diego - Catalina voyagers.. if they have time constraints..... simply motorsail the 70nm up overnight during calmer evening conditions.
14 to 16 hours overnight puts them in Avalon around noon to pick up a mooring, R&R, then go ashore for a nice dinner... the return trip is most likely a comfortable run back home. This was the M.O. for my last trip and we flew the spinnaker for 55 or the 65nm back to Mission Bay. Great fun!