If you open the spigot in the manifold, you'd better be prepared to put the bilge cover in place quickly. The water will come out of that spigot at a high rate of pressure. I have the three-tank set-up on my 350. My dealer recommended draining the tanks through the faucets in the sinks. That way, you are sure to clear out the anti-freeze in the tanks. It takes longer, but you can do other work while the tanks are draining.