Rest assured Roger, on your trip down the ICW you Will run aground, probably in soft mud. In the Albemarle Sound, Pamlico Sound, Pamlico and Neuse Rivers and tributary creeks there is little to no tide range. Fluctuations in water level are dependent on wind direction. Cuts from one creek to another are generally thru harder ground and less prone to shoaling. From Beaufort/Moorehead City NC on you will again encounter tides, ranging from a couple feet at Moorehead City to as much as nine feet at Beaufort SC.
You will probably have the greatest pucker factor as you go through the "rock pile" near Myrtle Beach.
Crossing inlets exposes you to the greatest probability of striking a shoal, most likely sand.
You can find nearly new updates on problem areas on web sites such as Claibourne Young's "Salty Southeast" Cruiser's Net. Also consider getting on the distribution list of LNM's from USCG 5th and 7th Districts.
Southbound we encountered no problems, Oriental NC to Ft.Lauderdale.
Northbound we bumped crossing Matanzas Inlet, St.Augustine Inlet, Lockwood's Folly, and Sneed's Ferry, none of which required any assistance getting off, but Boat US Unlimited was available if it had been needed.