Bleeding
To my way of thinking, having to bleed the air out of the fuel system by cracking each injector line, cranking the engine, etc, etc. would be such a pain in the ass that I never want to go there if I can avoid it. On my boat (H340), with an 3GM30F engine, the tank is above the primary filter so I purge the filter using gravity and the bleed screw on top when I change the filter as alexco38 suggests. I always change my secondary filter at the same time and then make sure I bleed the air from both the filter and the line going to the injector pump. Plenty of pumping to make sure I have no air in the system. What do they say about an ounce of prevention...?