Stu,
Just asking. No two batteries are ever exactly alike. The internal resistance of one is always going to be a bit different then the other. One will always be able to deliver more current, under load, than the other in series. One will charge and top off before the other. Back in the day, when I was young, I worked in a plant that made Sears Die Hard Batteries. One of my jobs was to test how well the burp valves worked by overcharging the battery in a chamber and igniting the vented hydrogen to ensure the subsequent fire didn't back into the cell being overcharged.
I presume the differences will be slight and all OK, as evidenced by many who have used such a battery bank.
Just trying to learn.
Cheers
I know a lot of answers have been provided but saw one details missing.
To best deal with the issue you have pointed out, it is important that all batteries that are placed into a bank are done so at the same time. I know Maine Sail has pointed this out before but I don't have a link readily available.
So if you are going to replace your two 4Ds with four 6V GCs, then buy all four at the same time. Go a step further and make sure you have four with matching date codes.
When I did this at Sam's Club it took about 5 minutes of looking around to find the four newest batteries with matching date codes.
One other quick note. If we weren't going cruising and were just using our boat for weekends with the occasional 1-2 week cruise with her spending the rest of the time on the dock hooked up to shore power, I would not get all of these batteries. Why purchase 4 batteries when a good setup (i.e. alternator direct with ACR, battery monitor on primary, etc.), a primary bank of two 6V GCs of 230 Ah and a reserved bank of one 12V group 24 would be perfectly adequate for that use. You could save a lot of money, weight and space and still have more actually battery capacity and cycles then you do with two 4Ds tied up in parallel. As Maine Sail has pointed out, the 4Ds are only about 160 Ah when new and they are not true deep cycle. Which means in a real world you only have about 100-130 Ah of usable capacity from two 4Ds in parallel. You would get close to the same from the two 6V CGs in series.
Good luck and fair winds,
Jesse