Pete,
There are two types of polyester resin used in building a boat, laminating and finishing. The hull is laid up with a laminating resin which cures with a tacky feel as it needs to be air inhibited to fully cure. The last layer or two applied to the mold will be laminated with a waxed finishing resin which will cure in air because the wax rises to the surface to seal if from the air.
Before any repairs can be done on older fiberglass, no matter how old, the first thing to do is a thorough dewax with a dewaxer like Interlux 202 or Pettit Dewaxer. Use only clean rags and a one wipe, fold, turn, one wipe fold turn, then a new rag approach. The dewaxer will soften the wax and transfer it to the rag but if you take more than one wipe you just wind up moving it around. Once dewaxed a thorough sanding of the area with 80 grit or better, then a final dewax, will give a good solid bond. These days I generally use my Fein Multi-Master with the diamond grit sanding / grinding blade as it can get into some very tight spots.
I have seen 35 year old hulls still beading water due to wax residue from manufacturing. If the interior of your boat is gelcoat then this should also be cleaned and sanded away down to the glass underneath it as seen above.
Sanding alone only serves to drive the wax into the substrate and makes it tougher to get out of the substrate for a good bond. When I used to sit in on surveys with my friend Brian one thing we saw often was failed secondary bonds, usually tabbing, or things like bulkheads & lazarette false floors tabbed in and added after the hull was cured etc..
Acetone can work as a dewaxer, as Ross mentioned, but I find Interlux 202 or Pettit Fiberglass Dewaxer work much better. I have tried to duplicate the secret "Frosted Flakes" recipe,

mixing my own solvents, but have not yet come up with one that works better than the Pettit or Interlux dewaxers.