Every now and then I come across someone who uses it and loves it...however I have no idea what they expect of it. Its sole purpose is to break down all the stuff--toilet waste, bath water, grease and all the other stuff that goes down kitchen sinks, toilet paper etc etc etc and emulsify sludge. So it should help to prevent sludge in your holding tank, but because odor prevention isn't a concern in septic tanks, it's not formulated to do that.. The active ingredient is enzymes which won't harm anything in your onboard sanitation system. So you have nothing to lose by trying it, but don't be too disappointed if it doesn't prevent odor out the tank vent.