Depends on boat performance & crew stamina
We "bashed" our Hunter Legend 43 back to Santa Barbara in 1993 without problems. However, we had good upwind performance (fully battened new main with 2nd and 3rd reef points), an inner staysail, a reliable Yanmar engine and two collapsible 35 gallon diesel bladders, all of which were essential to keep "powerpointing" (motorsailing) into wind and waves. Also, we had a crew of 3 (4 may be preferable, as there is likely to be a lot of handsteering unless you have an autopilot or windvane that can reliably steer an apparent wind angle of 20-30 degrees).We only stopped in Turtle Bay to refuel and in San Diego to clear back in, (don't forget to do that even if your are headed for SF, unless you are more than 200 NM offshore, or else you might be treated roughly on suspicion of drug running and fined thousands of $$). Expect lots of poorly lit shrimping vessels, fishing nets and insetting currents (with the risk of being "embayed", e.g. south of Turtle Bay), as well as all manner of large freighters, cruise ships and naval vessels.Also, make sure to return before June as cyclones tend to be early in southern Baja and may keep you locked in the Sea of Cortez for days or weeks (unless they are now operating the planned overland vessel transit across Baja, about halfway up).At the time we thought it was all great fun since it was our first long coastal trip and we were learning new tricks every day. Now, we would opt for going at least 300 NM offshore, depending on wind and weather, in order to avoid all coastal hazards and leave plenty of searoom. In fact, it has often been suggested that this offers the perfect opportunity to visit Hawaii on the way back....... just make sure you don't do that in a full-fledged El Nino year or you might not find any tradewinds (as happened to us in May 1997).Alternatively, why come back at all? There is plenty of space in the new marina in San Carlos and your boat will be taken care of like royalty by people like Abel Anaya (the skipper of Miss Teton) and his family for a very reasonable fee. San Carlos is far enough North to have low cyclone risk (i.e. acceptable to most insurers) and you can drive there from Phoenix in about 12 hours, or so. We liked it so much there that we barely managed to escape after 2 years. It was "now or never" or we would still be sipping Margueritas and listening to Jimmy Buffet tapes instead of visitng the South Pacific.........

))Whatever you decide, by all means DO GO! The Sea of Cortez is worth all the trouble. Where else do you have a chance to swim with sea lions, dolphins, whales, hammerheads, whale sharks and manta rays while catching plenty of dorado, wahoo, tuna, squid and lobster and beachcombing for exotic shells (not to mention the food, drinks, music and friendly people), all in the same place? Good luck and fair winds!Flying Dutchman"Rivendel II" (currently dry-berthed for the S. Pacific cyclone season in Vuda Point Marina,Fiji)