It depends on the angle and the fittings locations
If you have enough clearance above the tank to spec all the fittings on the top of the tank, with a pickup tube inside the tank, it won't matter what the angle is as long as the discharge is is directly above the lowest point in the tank. But if the discharge fitting is at the bottom of the tank, you'd have to put it at the low side.If you've bought an "off the shelf" rectangular tank that already has fittings installed in the so-called "standard" locations (all on one end), your best option would prob'ly be to return it and order a non-rectangular tank (triangular?) that fits your space. Ronco Plastics http://www.ronco-plastics.com is your best source. They make TOP quality thick-walled rotomolded poly tanks for a very reasonable price and have more than 400 shapes and sizes, including over 100 non-rectangular (that include triangular to lie along the hull). And they install fittings in the sizes and locations specified by the customer when they make the tank.And btw...if the tank is to lie along the hull, spec your vent and discharge fitting to be toward the centerline of the boat...to prevent spillage out the vent and waste running back toward the toilet when the boat is heeled.Before tackling this project, you might want to check out the link below.