Sounds like a blocked tank vent...but..
When air can't replace waste being pulled out, the pumpout or macerator pulls a vacuum and cannot pull anything out. Same is true in reverse...if air displaced by contents added to the tank has no where to escape, it leaves no room for anything to be added to the tank. Catalina vents holding tanks into a rail stanchion...the only source of air in or out is a very small slit in the stanchion. I suspect that you'll find that slit is complete plugged. Clean it out and it should clear the vent. However, although that's the mostly likely place, it may NOT be...so proceed very carefully in trying to pumpout till you do find the blockage and clear it, because a really strong pumpout pulling against a blocked vent can crack a tank. But there may be another problem too: Are you sure the macerator is directly inline between the tank and the deck pumpout fitting, and not in a hose split off the pumpout hose going to a thru-hull? If it is inline to the deck pumpout fitting, it's a blockage in the pumpout hose that would prevent a pumpout from pulling anything out of the tank or any water from going down the pumpout hose past it. There's only two possible reasons why it would be installed that way: 1. the PO must have used it to dump the tank (illegally unless he was able to go out to sea at least 3 miles from the nearet point on the whole US coastline) through the deck fitting by attaching a hose to it that dangled over the side. 2. For some reason he felt that the pumpout needed assistance from a macerator to pull waste out of the tank--which should not be necessary. If the motor runs, but you still can't pump out while it's running, there are only two possibilities: a blocked tank vent is one...the other is a failed impeller in the macerator, which is not uncommon...any time a macerator is allowed to run dry, it'll fry the impeller. In either case, you don't need it. But if it really is inline with the deck pumpout fitting, you're faced with a conumdrum: unless the only problem is a blocked vent, you're not gonna be able to pumpout the tank till you either replace the impeller (why spend money on something you need to remove?), or remove it...but you can't remove it and replace the pumpout hose till the tank is empty and flushed out without dumping tank contents inside the boat. Pray that your only problem is a blocked vent. If it's not, and if there's no inspection port in the tank that you can stick the pumpout directly into to pumpout the tank, I think you're gonna need some help from your local boatyard.