Good question.
Most likely, no. But the answer would involve performing the sizing calculations based on box size and amount of insulation.
With great insulation? Maybe. With OEM "non" insulation, it's a stretch at best.
Good luck.
The dry box is about 2 cu ft. The current refrigerator area is about 3. The manual for the Cold Machine says the small evaporator we have should work for 4” insulated boxes with a small freezer section of up to 9 cu ft total. Based on this information, my existing hardware and boxes should work. I’m going for it as everything is already out.
What's the amperage draw for the Cold Machine? Is it the potential battery draining monster?
yes, refrigeration is power hungry. The plate on the Cold Machine in our 2004 310 says 5 amps. That’s running. So daily use depends on the amount of run time. At 100% all day it would pull about 120 total amps. The Isotherm in my former boat freezing 3 cu ft and cooling 4.5 cu ft with four people cruising in the Bahamas used about 80 amps per day. We had 2 x 150 watt solar panels that gave us about 75 amps of total power per day. Sometimes more.
If you look at the time and cost to convert the dry box to a cooler you may want to look at just buying a 12 volt cooler. That's what we did the cooler cost $125 and I used a $10 controller to maintain the temp. To convert the box I would have to drill a 2.5" hole in add a fan and a controller for the fan to maintain a temp and that's with out adding foam insulation and taking every thing apart.
Hi Leo. Thanks for response. Dometic’s instructions call for a 3” hole 1/2 way down the dry box freezer compartment with a 1” spillover across the top. No fan is necessary. I lived with a similar set up in my previous boat for a year with 4 of us. We could go almost three weeks without re provisioning. We also ate meat every night. Not much fish as we didn’t catch much.

The amount and type of insulation is still unknown. When I drill the 3” hole between the spaces, I’ll let everyone know what I find. Not interested in any more crap laying around inside. Moving down from a 41’ ketch is making storage a challenge.