As usual it depends. For small blisters especially if there are few, I've had good success just scraping them out and filling them with thickened epoxy. The biggest challenge is to get rid of the moisture in the glass. Some have suggested 3 to 6 months on the hard, but where we live that would take out an entire sailing season because 3 months is our dry season. So I used a heat gun (careful to not get it too hot, a hair dryer may make more sense but I haven't tried that.) and went ahead and filled it. Next I just applied bottom paint. I haul every 2 years and it still looked okay. Our current boat only had a dozen dime size or smaller and none had cracked so I left them and repainted.
Ken