Other choices
The Sea of Cortez is a great place to explore. But, be prepared to be self-sufficient. There are launch ramps at Loreto, Puerto Escondido, La Paz, and Cabo San Lucas, among other places. The drive CAN be challenging, as has been stated. It might be easier to cross the border at Nogales, in Arizona, and then drive for only five to six hours to San Carlos, on the mainland side of the Sea. It is a good four lane highway, and there are excellent launching facilities at Marina San Carlos. From there, you can explore the eastern side, or sail about ninety miles across to the Baja side. YOu will have a great time, but experience (of which you will gain quite a bit!) is very helpful. The weather can be very variable, anything from a blistering calm to the occasional hurricane. The winter features frequent Northers, which can blow quite steadily and hard. The summer is much calmer, but is the storm season. If you want, email me at tims@cabomarina.com.mx and I will try to answer any questions. For reference, I have been down here for more than ten years and am currently the Dockmaster at Cabo Marina.