How big is your fuel tank?
Just kidding, My fuel tank has a round fitting on top that contains the fuel gauge sender, gasketed and secured with about six small bolts. That provides an access port that is about four inches (10 cm) in diameter. The tank itself is plastic, and with the sealant, it does not want to come apart easily.
I have not installed any other access to the tank, but as long as you have a relatively flat surface, it would be possible to provide a bigger opening. In my opinion though, that would just make another potential leak if it could not be properly sealed.