I'd wait until it is in the water.
Trent:I have not tried to do this myself but If you have NOT filled the line with water I seriously doubt that it will suck up water without the line being primed.This was discussed several months ago. When the boat is back in the water the system will try to force water up to the pump and my bet is that it will start pumping just fine.Like the others pointed out, even if it is a new impeller it may be old and not flexible enough to pump properly. I would just wait until the boat is splashed and see what happens. You can always get another impeller and you will be ready to change it if something does not work once you in the water.