It's different for everybody. We live in Florida, but we're 300 miles from Miami, and 40 miles inland from the nearest salt water, which is Cedar Key. So I am about as well situated as one can be in this state.
That said ... in the event that Irma entered the Gulf of Mexico still relatively undiminished, and took aim at the Gulf coast north of Tampa, I would have some very real cause for concern, even here. Never mind the boats in the driveway - I live in an early 90's mobile home, not much sturdier than a canvas tent, and I'm surrounded by massive trees that would crush anything they might fall on.
I'll have a plan in motion by tomorrow AM if Irma looks like she's heading for the Gulf.